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Tomas Simurda Selected Research

Afibrinogenemia (Fibrinogen Deficiency)

2/2022Heterogeneity of Genotype-Phenotype in Congenital Hypofibrinogenemia-A Review of Case Reports Associated with Bleeding and Thrombosis.
11/2021Congenital Afibrinogenemia and Hypofibrinogenemia: Laboratory and Genetic Testing in Rare Bleeding Disorders with Life-Threatening Clinical Manifestations and Challenging Management.
4/2021Use of Fibrinogen Determination Methods in Differential Diagnosis of Hypofibrinogenemia and Dysfibrinogenemia.
12/2020A Novel Nonsense Mutation in FGB (c.1421G>A; p.Trp474Ter) in the Beta Chain of Fibrinogen Causing Hypofibrinogenemia with Bleeding Phenotype.
7/2020Congenital hypofibrinogenemia associated with a novel heterozygous nonsense mutation in the globular C-terminal domain of the γ-chain (p.Glu275Stop).
12/2017Identification of Two Novel Fibrinogen Bβ Chain Mutations in Two Slovak Families with Quantitative Fibrinogen Disorders.
9/2016Perioperative Coagulation Management in a Patient with Congenital Afibrinogenemia during Revision Total Hip Arthroplasty.
6/2016Fibrinogen Martin: A Novel Mutation in FGB (Gln180Stop) Causing Congenital Afibrinogenemia.
11/2015Novel fibrinogen bbeta chain mutation as an underlying mechanism of afibrinogenemia?

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Tomas Simurda Research Topics

Disease

9Afibrinogenemia (Fibrinogen Deficiency)
02/2022 - 11/2015
5Hemorrhage
02/2022 - 06/2020
3Thrombosis (Thrombus)
04/2022 - 06/2020
2von Willebrand Diseases (von Willebrand's Disease)
11/2021 - 06/2020
1Protein S Deficiency (Deficiency, Protein S)
04/2022
1Disseminated Intravascular Coagulation
04/2021
1Asymptomatic Diseases
06/2020
1Congenital Abnormalities (Deformity)
06/2020
1Infections
06/2020
1Inflammation (Inflammations)
06/2020
1Neoplasm Metastasis (Metastasis)
06/2020
1Disease Progression
12/2017
1Type 3 von Willebrand Disease
01/2017

Drug/Important Bio-Agent (IBA)

7Fibrinogen (Factor I)FDA Link
02/2022 - 06/2016
3von Willebrand FactorIBA
11/2021 - 01/2017
2Nonsense Codon (Nonsense Mutation)IBA
12/2020 - 07/2020
1Protein CIBA
04/2022
1Protein SIBA
04/2022
1AntithrombinsIBA
04/2022
1AnticoagulantsIBA
04/2022
1Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
11/2021
1Factor XIII (Coagulation Factor XIII)IBA
06/2020
1FibrinIBA
06/2020
1Fibronectins (Fibronectin)IBA
06/2020
1PlasminogenIBA
06/2020
1PolymersIBA
06/2020
1VitronectinIBA
06/2020
1Blood Coagulation Factors (Coagulation Factor)IBA
06/2020
1Proteins (Proteins, Gene)FDA Link
06/2020
1BBeta fibrinogenIBA
11/2015

Therapy/Procedure

1Thrombolytic Therapy
04/2021
1Hip Replacement Arthroplasty (Total Hip Replacement)
09/2016